________you may have，you should gather ...

________you may have，you should gather your courage to face the challenge.

A．However a serious problem

B．What a serious problem

C．However serious a problem

D．What serious a problem

C 【解析】考查状语从句。分析题干可知逗号前是让步状语从句，what不能用来引导状语从句，所以排除B、D两项；however＋adj.＋a/an＋单数名词＝whatever＋a/an＋adj.＋单数名词，句意：不论你的问题有多严重，你都应该鼓起勇气，接受挑战。故C项正确。

考点分析：

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