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His efforts to raise money for his prog...

 His efforts to raise money for his program were ______ because, no one showed any intention to take a cent out of their pockets.

A. in place      B. in sight          C. in effect         D. in vain

 

 D. 【解析】考查介词短语。根据下文no one showed any intention to take a cent out of their pockets可知为集资做出的努力都白费了,应选择in vain。in place“和平地”,in sight“在视程内”,in effect“实际上”。
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