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As we know many seccessful people never ...

As we know many seccessful people never          no matter what difficulties they have had.

A.stay up B.give up C.cheer up

 

B 【解析】 句意:众所周知,许多成功人士无论遇到什么困难他们都不会放弃。 考查动词短语。stay up熬夜;give up放弃;cheer up振作,打起精神。根据“no matter what difficulties they have had”可知,此处表达的是“许多成功人士无论遇到什么困难,他们都不会放弃”。故选B。
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